Structural Biology
Structural Biology is pivotal for understanding molecular recognition in biological systems at atomic resolution since small ligands (e.g., drugs) interact in most cases with biological macromolecules. Hence, having a structural description of the biological macromolecule at hand allows one to understand the mode of operation of the drug which in turn paves the way for its rational redesign, a powerful paradigm for biomedical research in the 21st century. The group includes two sub-groups, the Hauptman Woodward Medical Research Institute (HWI) pursuing X-ray crystal structure analyses, and NMR-based structural biology/genomics pursued in the Chemistry Department.
