What is Molecular Recognition in Biological Systems and Bioinformatics (MRBSB)?
Molecular Recognition in Biological Systems (MRBS) is dedicated to understanding the fundamental biology and molecular nature of disease by using small molecules, molecular structures, and pharmacodynamic approaches to understanding the complex nature of biological systems. Interactions of macromolecules with each other, and with natural and designed small molecule ligands, and how small molecules interact with and regulate the interactions of proteins, DNA, RNA, and other cellular components to modulate biological processes are central to this understanding. This is the unifying principal of our group, which brings together several areas of excellence across the university and focuses on medically relevant research at the interface of chemistry and biology.
Knowledge of the molecular basis of biological processes is of central importance to the understanding and treatment of disease and the design of new therapeutic interventions. Very productive UB research programs contribute to this area of excellence.
Each group, as identified above, includes a strong base of faculty who have well-funded, interconnected, and interdepartmental research programs. The major strengths of the existing centers also include their inter-related member lists; their history of collaboration (evidenced by regular research meetings, joint publications, and extramural funding); and a considerable degree of overlap among their research interests. These connections offer strong possibilities for growth of the area overall, as well as the potential to diversify into newly emerging fields. Additionally, opportunities for collaborative funding of research and training among the interdisciplinary group members are excellent.
