Integrated Nanostructured Systems

Tapping mode AFM images: (a) height image of brush copolymer on mica, (b) phase image of brush copolymer on mica, (c) height image of amphiphilic brush copolymer on silicon, (d) phase image of amphiphilic brush copolymer on silicon, (e) 3D height image of peripherally cross-linked brush copolymer on mica, (f) 3D height image of hollowed nanostructure on mica.

Synthesis and characterization of polymers; synthesis and characterization of organic/polymer nanostructures; biomedical applications of biodegradable functional polymers and nanostructures.

In recent years, Cheng et al. have developed a new synthetic method of polymeric nanomaterials by selective crosslinking of brush copolymers. Cheng et al. have also established new and facile synthetic strategies of brush copolymers, hyperbranched fluoropolymers, and various functional polymers. At UB, Cheng's group focuses on the development of general methodologies for the preparation of well-defined biodegradable functional polymers and nanostructures, which can further serve as templates for biomedical and bioengineering applications, especially drug delivery and tissue engineering.

Gel permeation chromatography (will be purchased)

"Well-Defined Vinyl Ketone-Based Polymers by Reversible Addition-Fragmentation Chain Transfer Polymerization"
Cheng, C.; Sun, G.; Khoshdel, E.; Wooley, K. L. J. Am. Chem. Soc.; (Communication); 2007; 129(33); 10086-10087.
http://dx.doi.org/10.1021/ja073541y

"Synthesis of Core-Crosslinked Nanoparticles with Controlled Cylindrical Shape and Narrowly-Dispersed Size via Core-Shell Brush Block Copolymer Templates"
Cheng, C.; Qi, K.; Germack, D. S.; Khoshdel, E.; Wooley, K. L.
Advanced Materials; 2007; 19(19); 2830-2835.
http://dx.doi.org/10.1002/adma.200602986

"Polydimethylsiloxane- (PDMS-) Grafted Fluorocopolymers by a "Grafting through" Strategy Based on Atom Transfer Radical (Co)polymerization"
Cheng, C.; Powell, K. T.; Khoshdel, E.; Wooley, K. L.
Macromolecules; 2007; 40(20); 7195-7207.
http://dx.doi.org/10.1021/ma070845w

"Complex Amphiphilic Hyperbranched Fluoropolymers by Atom Transfer Radical Self-Condensing Vinyl (Co)polymerization"
Powell, K. T.; Cheng, C.; Wooley, K. L.
Macromolecules; 2007; 40(13); 4509-4515.
http://dx.doi.org/10.1021/ma0628937

"Reversible Addition Fragmentation Chain Transfer Polymerization of 4-Vinylbenzaldehyde"
Sun, G.; Cheng, C.; Wooley, K. L.
Macromolecules; (Communication); 2007; 40(4); 793-795.
http://dx.doi.org/10.1021/ma062592x

"One-Pot Tandem Synthesis of a Core-Shell Brush Copolymer from Small Molecule Reactants by Ring-Opening Metathesis and Reversible Addition-Fragmentation Chain Transfer (Co)polymerizations"
Cheng, C.; Khoshdel, E.; Wooley, K. L.
Macromolecules; (Communication); 2007; 40(7); 2289-2292
http://dx.doi.org/10.1021/ma0627525

"Hyperbranched Fluoropolymers and their Hybridization into Complex Amphiphilic Crosslinked Copolymer Networks"
Bartels, J. W.; Cheng, C.; Powell, K. T.; Xu, J.; Wooley, K. L.
Macromolecular Chemistry and Physics; 2007; 208(15); 1676-1687.
http://dx.doi.org/10.1002/macp.200700104

"Tandem Synthesis of Core-Shell Brush Copolymers and Their Transformation to Peripherally Cross-Linked and Hollowed Nanostructures"
Cheng, C.; Qi, K.; Khoshdel, E.; Wooley, K. L.
J. Am. Chem. Soc.; (Communication); 2006; 128(21); 6808-6809.
http://dx.doi.org/10.1021/ja061892r

"Facile One-Pot Synthesis of Brush Polymers through Tandem Catalysis Using Grubbs' Catalyst for Both Ring-Opening Metathesis and Atom Transfer Radical Polymerizations"
Cheng, C.; Khoshdel, E.; Wooley, K. L.
Nano Lett.; (Letter); 2006; 6(8); 1741-1746.
http://dx.doi.org/10.1021/nl0611900

"Complex Amphiphilic Networks Derived from Diamine-Terminated Poly(ethylene glycol) and Benzylic Chloride-Functionalized Hyperbranched Fluoropolymers"
Powell, K. T.; Cheng, C.; Wooley, K. L.; Singh, A.; Urban, M. W.
Journal of Polymer Science Part A: Polymer Chemistry; 2006; 44(16); 4782-4794.
http://dx.doi.org/10.1002/pola.21576

"ATRP from a Norbornenyl-Functionalized Initiator: Balancing of Complementary Reactivity for the Preparation of -Norbornenyl Macromonomers/-Haloalkyl Macroinitiators"
Cheng, C.; Khoshdel, E.; Wooley, K. L.
Macromolecules; 2005; 38(23); 9455-9465.
http://dx.doi.org/10.1021/ma0515984

"Hyperbranched Fluorocopolymers by Atom Transfer Radical Self-Condensing Vinyl Copolymerization"
Cheng, C.; Wooley, K. L.; Khoshdel, E.
Journal of Polymer Science Part A: Polymer Chemistry; 2005; 43(20); 4754-4770.
http://dx.doi.org/10.1002/pola.20987

"Design, Synthesis, and Characterization of Linear Fluorinated Poly(benzyl ether)s: A Comparison Study with Isomeric Hyperbranched Fluoropolymers"
Powell, K. T.; Cheng, C.; Gudipati, C. S.; Wooley, K. L.
Journal of Materials Chemistry; 2005; 15; 5128-5135.
http://dx.doi.org/10.1039/b511555h

"Synthesis of a Novel Polyfunctional Anionic Macroinitiator from a Polyfunctional 1,1-Diphenylethylene Agent"
Cheng, C.; Yang, N.-L.
Macromolecular Rapid Communications; 2005; 26(17); 1395-1399.
http://dx.doi.org/10.1002/marc.200500349