Integrated Nanostructured Systems

Examples of xerogel-based monoliths, thin films, and arrays.

Development of new materials based on sol-gel-derived xerogels; investigations into the molecular-level phenomena that govern the material characteristics and behavior.

Our recent research has focusd in two areas: (i) new molecularly templated xerogel platforms for the detection of medium-sized molecules (e.g., drugs) and proteins and (ii) new hybrid, thin film platforms that exhibit minimal fouling in fresh water and marine applications.

Laser-induced photoluminescence (steady-state, time resolved, and imaging)

Y. Tang, J.A. Finlay, G.L. Kowalke, A.E. Meyer, F.V. Bright, M.E. Callow, J.A. Callow, D.E. Wendt and M.R. Detty*, "Hybrid Xerogel Films as Novel Coatings for Antifouling and Fouling Release," Biofouling 2005, 21, 59-71.

Z. Tao, E.C. Tehan, R.M. Bukowski, Y. Tang, E.L. Shughart, W.G. Holthoff, A.N. Cartwright, A.H. Titus and F.V. Bright*, "Templated Xerogels as Platforms for Biomolecule-less Biomolecule Sensors," Anal. Chim. Acta 2006, 564, 59-65.

E.L. Shughart, K. Ahsan, M.R. Detty and F.V. Bright*, "Site Selectively Templated and Tagged Xerogels for Chemical Sensors," Anal. Chem. 2006, 78, 3165-3170.

E.C. Tehan, D.J. Higbee, T.D. Wood and F.V. Bright*, "Tailored Quartz Pins for High-Density Microsensor Array Fabrication," Anal. Chem. 2007 79, 5429-5434.

E.L. Holthoff and F.V. Bright*, "Molecularly Templated Materials in Chemical Sensing," Anal. Chim. Acta 2007 594, 147-161.

E.L. Holthoff and F.V. Bright*, "Molecularly Imprinted Xerogels as Platforms for Sensing," Acc. Chem. Res. 2007 40, 756-767.